APPA reduces senescence & reactive oxygen species production

New data presented at the European League against Rheumatism (EULAR) demonstrates that APPA reduces the number of senescent chondrocytes, and inhibits ROS production in human articular chondrocytes. Today AKL Research & Development unveils new data at the Virtual European Congress of Rheumatology (EULAR) 2021 (June 2-5). Findings from the study indicate our investigational oral osteoarthritis […]

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New studies suggests APPA protects against joint damage

Today sees the unveiling of new data at the Osteoarthritis Research Society International (OARSI) Virtual World Congress (April 29 – May 1) indicating investigational oral osteoarthritis (OA) drug APPA can modulate cellular function, reduce inflammation and inhibit bone resorption associated with joint degradation caused by the disease. Read full press release. Characterizing the effect of […]

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Personalised Medicine & Disease Modification in OA

In this article we discuss the challenges in demonstrating disease modification in OA, illustrate this with examples of recently published clinical trials, and describe the current status of APPA, a novel, patented potential Disease Modifying Osteoarthritic Drug (DMOAD).

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