Today sees the unveiling of new data at the Osteoarthritis Research Society International (OARSI) Virtual World Congress (April 29 – May 1) indicating investigational oral osteoarthritis (OA) drug APPA can modulate cellular function, reduce inflammation and inhibit bone resorption associated with joint degradation caused by the disease. Read full press release.
Biological effect of APPA in human articular chondrocytes. Fernandez-Moreno M, Larkins N, Reynolds A, Hermida-Gomez T, Blanco FJ. Osteoarthritis and Cartilage 2021; 29 (supplement1): S358 Abstract 432.
Characterizing the effect of APPA on tissue turnover in cartilage and bonetissue cultures. Thudium CS, Bay-Jensen AC, Gantzel T, Dziegiel M, Larkins N, Reynolds A. Osteoarthritis and Cartilage 2021; 29 (Supplement1): SS152 Abstract 83.